The non heart-beating donor

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Non-Heart-Beating Donor Heart Transplantation: Breaking the Taboo

Roughly 60% of hearts offered for transplantation are rejected because of organ dysfunction. Moreover, hearts from circulatory-dead patients have long been thought to be non-amenable for transplantation, unlike other organs. However, tentative surgical attempts inspired by the knowledge obtained from preclinical research to recover those hearts have been performed, finally culminating in clinic...

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Preliminary results of heart-beating and non-heart-beating donor kidney transplants--the Singapore experience.

Renal transplantation is the ideal renal replacement therapy for treatment of end stage kidney failure but its limitation is the constant shortage of cadaveric donors. While the traditional source of cadaveric kidneys is procurement from heart-beating donors, organ procurement from non-heart-beating donors (NHBD) would help in coping with the rising demand for organs. However various important ...

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Comparative study of donor lung injury in heart-beating versus non-heart-beating donors.

OBJECTIVE The use of non-heart-beating donors (NHBD) has been advocated as an alternative to overcome the critical organ shortage in lung transplantation despite the warm ischemic period that may result in primary graft dysfunction. On the contrary, brain death in the heart-beating donor (HBD) may be an underestimated risk factor for donor lung injury. We postulated that 60 min of warm ischemia...

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Non heart beating organ donor: new experimental model in pigs.

PURPOSE To describe technical aspects of a new experimental model that simulates a non heart beating organ donor. METHODS Landrace pigs were operated on and cardiac arrest was obtained by means of myocardial infarction and interruption of ventilator support. RESULTS Mean cardiac frequency, systolic and diastolic blood pressure levels, central venous pressure, oxygen saturation and concentra...

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Non-heart beating donors.

BACKGROUND Several groups have demonstrated that non-heart beating donation is a viable source of organs for transplantation. However, the theoretically worse graft function and survival of the kidneys obtained from non-heart beating donors (NHBDs) is still a matter of debate that has led to consider them as marginal donors for kidney transplantation. METHODS In this report, we compare the ou...

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ژورنال

عنوان ژورنال: British Medical Bulletin

سال: 1997

ISSN: 0007-1420,1471-8391

DOI: 10.1093/oxfordjournals.bmb.a011652